Panretin (Alitretinoin): Uses Dosage Side Effects

Patients who are applying Panretin gel should not concurrently use products that contain DEET (N N-diethyl-m-toluamide) a common component of insect repellent products Animal toxicology studies showed increased DEET toxicity when DEET was included as part of the formulation

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Pharmacology of Pesticides

Mechanism of Action These drugs act by slowing closure of the excitable membrane ion channels opened during action potentials so that there are multiple action potentials Sulfur compounds Elemental sulfur (sublimed sulfur) and its preparations the most common of which is Lime-Sulfur are frequently used to control ectoparasites The

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Diethylamine

RISK: Diethylamine is an eye nose and lungs irritant Serious eye skin and lung damage can occur at high vapor exposure levels or following direct contact with liquid diethylamine resulting in blurred vision burns and/or difficulty breathing Data on the potential for diethylamine to produce other toxic effects in humans were not

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DEET

REDUCING THE RISK OF MOSQUITO BITES is currently the only way to reduce the risk of West Nile virus infection Methods for avoiding mosquito bites include limiting the time spent outdoors at dawn and dusk wearing protective clothing and using an insect repellent Repellents containing DEET (N N-diethyl-m-toluamide also known as N N-diethyl-3-methylbenzamide) are the

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Indoor residual spraying with

Evolution of insecticide resistance in Anopheles gambiae complex necessitates evaluation of alternative chemical classes to complement existing insecticides for long lasting insecticidal nets (LLIN) and indoor residual spraying (IRS) Microencapsulated (MC) DEET (N N-diethyl-m-toluamide) is a formulation of the popular repellent which gives long lasting activity when

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Dermatological Pharmacology

principles of dermatological pharmacology The skin is a biologically active multifunctional and multicompartment organ Medications can be applied to the skin for two purposes: to directly treat disorders of the skin and to deliver drugs to other tissues

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See other formats

Absorp- Species deet formulation Acetone solution Dose Dose site Quantitation tion 2 % Reference Human 4 u g/cm 2 Ventral forearm Radioactivity 16 7 3 Feldmann and Mai- (n = 4) ( l4 C-labeled) bach (1970) Human Technical deet 0 625 mg/cm 2 Volar forearm Radioactivity 5 6 Selim et al (1995) (n = 6) (98 5% C-la- beled) Ethanol solution 0 5 mg/cm 2 Volar forearm

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Evidence for inhibition of cholinesterases in insect and

N N-Diethyl-3-methylbenzamide (deet) remains the gold standard for insect repellents About 200 million people use it every year and over 8 billion doses have been applied over the past 50 years Despite the widespread and increased interest in the use of deet in public health programmes controversies remain concerning both the identification of its target sites at the olfactory system

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Toxicity Assessment of Environmentally Relevant Pollutant

Toxicity Assessment of Environmentally Relevant Pollutant Mixtures Using a Heuristic Model Allen W Olmstead and Gerald A LeBlanc* Department of Environmental and Molecular Toxicology North Carolina State University Raleigh North Carolina 27695 USA

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Pharmacogenetics of cytochrome P450 2B6 (CYP2B6):

Cytochrome P450 2B6 (CYP2B6) belongs to the minor drug metabolizing P450s in human liver Expression is highly variable both between individuals and within individuals owing to non-genetic factors genetic polymorphisms inducibility and irreversible inhibition by many compounds Drugs metabolized mainly by CYP2B6 include artemisinin bupropion cyclophosphamide efavirenz

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Talk:DEET

mechanism and effectiveness section The prevailing theory was that DEET effectively blinds the insect's senses so that the biting/feeding instinct is not triggered by humans or other animals which produce these chemicals sounds overcomplicated to me i first misinterpreted the sentence as saying that there are animals that produce DEET to

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DEET

DEET (N N-diethyl-m-toluamide also known as N N-diethyl-3-methylbenzamide) is the most effective and most widely used insect repellent It was first used by the US military in 1946 and has been sold commercially for al-most half a century Products are available with concentra-tions of 5% to of DEET and come in a variety of

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ANALYSIS OF MOLECULAR STEREOELECTRONIC

APURBA K BHATTACHARJEE and RAJ K GUPTA ANALYSIS OF MOLECULAR STEREOELECTRONIC SIMILARITY BETWEEN N N-DIETHYL-M-TOLUAMIDE (DEET) ANALOGS AND INSECT JUVENILE HORMONE TO DEVELOP A MODEL PHARMACOPHORE FOR INSECT REPELLENT ACTIVITY Journal of the American Mosquito Control Association

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Cardiorespiratory Effects Following Acute Exposure to

The acute lethal interaction that occurs in rodents when high doses of a peripherally restricted cholinesterase inhibitor pyridostigmine bromide (PB) and the insect repellent N N-diethyl-m-toluamide (DEET) are combined was first described during studies of chemical mixtures that were targeted as potential causative agents of Gulf War illnesses

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Toxicity Assessment of Environmentally Relevant Pollutant

Toxicity Assessment of Environmentally Relevant Pollutant Mixtures Using a Heuristic Model Allen W Olmstead and Gerald A LeBlanc* Department of Environmental and Molecular Toxicology North Carolina State University Raleigh North Carolina 27695 USA

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The mysterious multi

studies showed that N N-diethyl-m-toluamide is safe for human use but it was recommended that ingestion be avoided 10 N N-diethyl-m-toluamide was renamed DEET by the Committee on Insecticide Terminology of the Entomological Society of Amer-ica because of "numerous complaints that diethyltoluamide was

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Preparation of N N

N N-Diethyl-m-toluamide (DEET) is the active ingredient in many insect repellants 1 In this experiment DEET will be prepared from m-toluic acid through the intermediate acid chloride and then identified by its IR and proton NMR spectra The overall reaction is a series of two acyl substitutions and is shown in Scheme 1 below: [pic] Scheme 1

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